Case Report: Identification of Two Rare Fusions, PDK1-ALK and STRN-ALK, That Coexist in a Lung Adenocarcinoma Patient and the Response to Alectinib

Several double ALK fusions coexisting in one patient have Cat Food been reported.However, few studies have reported the clinical efficacy of ALK inhibitors in rare double ALK fusions.Here, we described a rare PDK1-ALK, STRN-ALK double-fusion variant in a patient with metastatic lung adenocarcinoma.The patient responded well to alectinib CCTV Leads and access (600 mg) twice daily.This case shows a promising treatment option for patients with rare ALK double-fusion variants.